Elective Reversal (reversal needed within days)

• Hold day of procedure
• Once-daily regimens: ½ dose day prior
• BID regimen: Hold evening dose day prior

Urgent Reversal (not bleeding, reversal needed within hours)

• Wait 12-24 hrs if possible, otherwise consider protamine sulfate

Urgent Reversal (bleeding, reversal needed immediately)

• HASHTI
• Protamine sulfate: 1 mg per 1 mg Enoxaparin given in previous 8 hrs
• Consider rVIIa