Factor Category: Antithrombin III Deficiency - Rare

Antithrombin III Deficiency rEVO Biologics Standard t1/2HALF LIFE:50 IU/kg: 11.6 hours100 IU/kg: 17.7 hours Transgenic   Dosing Calculation Surgical patients:Loading dose:#Units = [100 – baseline AT activity / 2.3] X weight (kg) Maintenance dose (continuous infusion):#Units = [100 – baseline AT activity / 10] X weight (kg) Pregnant women:Loading dose:#Units = [100 – baseline AT activity / 1.3] X weight (kg) Maintenance dose (continuous infusion):#Units = [100 – […]

Antithrombin III Deficiency Grifols Standard t1/2HALF LIFE (days): 2.5-3.8 Plasma-derived   Dosing Calculation # Units = [100 – baseline AT activity / 1.4] X weight (kg) Dosing goal: 80-120% Notes:Monitoring antithrombin: Baseline level 20 minutes post-infusion Q 12 hrs Recommended Dosing Guidelines Regimen (timing) Target AT Level Dose (Units) Monitor AT Level Loading Dose 120% of normal [120% – […]