Biogen Extended t1/2IgG-1 Fc Domain Recombinant Fusion Protein 4th Gen HALF LIFE (hours):Adults: 87Peds:2 – 5 yrs: 66.46 – 11 yrs: 72.212 – 17 yrs: 83.6 Dosing Calculation # Units = weight (kg) X % correction* X VD*Written as Whole Number (50%=50) IU/kg (% correction) Patient < 12 yrs Patient ≥ 12 yrs Prophylaxis 60 Q 7 days 100 Q […]
Novo Nordisk Extended t1/2Glycopegylation Recombinant HALF LIFE (hours): 3rd Gen ≤6 yrs: 69.67-12 yrs: 76.3≤17 yrs: 89.4≥18 yrs: 83 Dosing Calculation Units = weight (kg) X % correction* X VD*Written as Whole Number (50%=50) IU/kg (% correction) Pediatric Adult Prophylaxis 40 IU/kg weekly 40 IU/kg weekly Minor Bleed (40%) (40%) Major Bleed (80%) (80%) Volume of Distribution ≤17 yrs 0.66 […]
CSL Bering Extended t1/2Albumin Fusion Protein Recombinant HALF LIFE (hours):Adults: 104 3rd Gen Peds:0 – 5 yrs: 906 – 11 yrs: 9312 – 17 yrs: 87 Dosing Calculation Units = weight (kg) X desired factor IX increase (IU/dL or % of normal) X VD (IU/kg per IU/dL)*Written as Whole Number (50%=50) Topic IU/kg (% correction) Patients <12 yrs Patients ≥ 12 […]
