Tranexamic Acid PAI-1 Deficiency Pfizer HALF LIFE:2-11 hours Dosing Calculation Topic Dose (oral) I.V. 10 mg/kg Q 6-8 hours Oral 25 mg/kg/dose (max 1.5 g/dose) Notes Do not use in the presence of hematuria or thrombosis. Generally not recommended for children <12 yrs. IHI does use in younger children based upon weight; discuss with treating […]
Tranexamic Acid PAI-1 Deficiency HALF LIFE: 2-11 hours Dosing Calculation Topic Dose (oral) Adult 1300 mg Q8 hours x 5 days Pediatric <12 yrs 15-20 mg/kg Q8 hours x 5 days Notes Do not use in the presence of hematuria or thrombosis. Generally not recommended for children <12 yrs. IHI does use in younger children […]
Aminocaproic Acid PAI-1 Deficiency HALF LIFE: 1-2 hours Various Manufacturers Dosing Calculation *Use adult dosing for children > 30 kg. Topic Dose (oral) Pediatric < 30 kg 100 mg/kg PO Q 6 hours Adult* > 30 kg 3 grams (6 tabs) PO QID while awake Topic Acute Bleeding Dose (I.V.) Loading 4-5 g during 1st […]
