FVIII & FIX Deficiency with inhibitors Takeda Standard t1/2HALF LIFE (hours): 4-7 hours;based on thrombin generation Plasma-derived(Activated PCC) Dosing Calculation Topic Dose Bleed 50-100 IU/kg Q 6-12 hours Prophylaxis 85 IU/kg every other day Administer dose over ~20-30 minutesMax single dose: 100 IU/kgMax daily dose: 200 IU/kg Notes Warning: Contains FIX. Patients with FIX […]