Factor Category: Standard t1/2 - FVIII

Nuwiq

Octapharma Standard t1/2 HALF LIFE (hours): Recombinant Adult: 17.2 (highly variable)Peds: 2-5 yrs: 11.9; 6-12 yrs: 13.1 4th Gen (BDD) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 […]

Kovaltry

Bayer Standard t1/2 HALF LIFE (hours): Recombinant Adult: ≥12 yrs: ~14.2-14.4Peds: 0-12 yrs: ~12 hrs 3rd Gen (FLC) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Notes *FDA […]

Xyntha

Pfizer Standard t1/2 HALF LIFE (hours): Recombinant Adult: 11.2 + 5Peds: 8 + 2.4 3rd Gen (BDD) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device […]

Novoeight

Novo Nordisk Standard t1/2HALF LIFE (hours): Recombinant Adult: 11-12Peds: 7.7-10 3rd Gen (BDT) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate at […]

Advate

Baxalta Standard t1/2HALF LIFE (hours): Recombinant Adult: 12Peds: 8.7-11.2 3rd Gen (FLC) *Per IHTC dosing:Half-life for all FVIII Standard t1/2 products: ~12 hours Dosing Calculation # Units = weight (kg) X % correction* X VD (0.5)*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Prophylaxis 3x/week: 25/25/50 (50%/50%/100%) Minor Bleed 20 (40%) Major Bleed 40 (80%) Transfer Device Storage Refrigerate at 2 […]