Octapharma (Vienna,Austria) Standard t1/2HALF LIFE (hours): 15.8Expressed in VWF:RCo units Plasma-derived VWF:FVIII = 1:1 *Per IHTC dosing:Half-life for all PD VWF products: ~ 12-18 hours Dosing Calculation # Units (VWF:RCo) = weight (kg) X %* correction X VD*Written as Whole Number (50%=50) Topic Dose VWF:RCo units/kg (% correction) Minor Bleed 20 (40%) Major Bleed 40 (80%) Prophy (Age 6 and older) […]
CSL Behring Standard t1/2HALF LIFE (hours): 10.5 Plasma-derived Expressed in VWF:RCo units VWF:FVIII = ~2:1 *Per IHTC dosing:Half-life for all PD VWF products: ~ 12-18 hours Dosing Calculation # Units (VWF:RCo) = weight (kg) X %* correction X VD*Written as Whole Number (50%=50) Topic Dose VWF:RCo units/kg (% correction) Minor Bleed 20 (40%) Major Bleed 40 (80%) Surgery (Loading) 50-60 Topic Volume […]
Grifols Standard t1/2HALF LIFE (hours):7.67 ± 3.32 Plasma-derived Expressed in VWF:RCo units VWF:FVIII = 1.3:1 *Per IHTC dosing:Half-life for all PD VWF products: ~ 12-18 hours Dosing Calculation # Units (VWF:RCo) = weight (kg) X %* correction X VD*Written as Whole Number (50%=50) Topic Dose VWF:RCo IU/kg (% correction) Pediatric Adult Minor Bleed 20 (40%) 20 (40%) Major Bleed 40 (80%) […]
Baxalta Standard t1/2HALF LIFE (hours): 19.1-21.9 Recombinant IU = Usually expressed in VWF:RCo units 3rd Gen Does not contain FVIII If needed, rFVIII dose:rFVIII IU = Vonvendi dose/1.3 Dosing Calculation # Units (VWF:RCo) = weight (kg) X %* correction X VD*Written as Whole Number (50%=50) Topic Dose IU/kg (% correction) Minor Bleed (Loading)* 40-50 (60-75%) Minor Bleed (Maintenance)* 40-50 (60-75%) […]
STAQ Pharmaceuticals Standard t1/2HALF LIFE (hours): ~12*Same as endogenous VWF Dosing Calculation Topic Dose (150 mcg/spray) <50 kg 1 spray >50 kg 2 sprays Notes Fluid restriction. Do not use in children <2 years of age. Use caution in pregnant women during labor and delivery, patients with cardiac disease or seizure disorder. *Spray pump must be […]
Ferring AB/U.S.Distributor Sanofi-Aventis Pharma Standard t1/2HALF LIFE (hours): 12*Same as endogenous VWF Dosing Calculation # mcg = 0.3 mcg/kg Topic Administration S.C. Injection Max volume 1.5 mL per syringe I.V. Mix in 30 ml NS administered over 30 min. Notes Max dose 24 mcg. May repeat after 24 hrs. Notes: Do not use in […]
