Mechanism of Action

• Anti-thrombin mediated inhibition of factor Xa

Half-Life

• 17-21 hrs

Metabolism

• Renal excretion

Dosing – Adult

• S.C.:
  • <50 kg: 5 mg daily
  • 50-100 kg: 7.5 mg daily
  • >100 kg: 10 mg daily

Dosing – Pediatric

• Please refer to pediatric section for information on use in children

Monitoring

• Not required.
• Can use: Antifactor Xa using drug specific curve