Mechanism of Action

• Glycoprotein IIb/IIIa receptor antagonist

Half-Life

• 2 hours

Excretion

• Urine (65%), Feces (25%)

Dosing – Adult

• I.V.: Loading dose: 25 mcg/kg administered over 5 min or less;
• Maintenance infusion: 0.15 mcg/kg/min continued for up to 18 hours

Dosing – Pediatric

• Safety and efficacy in pediatric patients not established

Onset & Duration of IPA

• Onset: >90% inhibition of platelet aggregation within 10 minutes