Perioperative Management

• Decision making regarding whether aspirin needs to be held depends on type of surgery, renal function, and balance of bleeding versus thrombosis risk. The duration for withholding is based upon the estimated platelet life span for high procedural bleeding risk. If it is indicated, aspirin should be discontinued at least 5-7 days prior to elective surgery or invasive procedures with a moderate or high risk of unacceptable or clinically significant bleeding.
• Restart aspirin after the procedure as soon as adequate hemostasis has been established and once cleared by the surgeon or interventionalist.