Currently, only Lovenox (enoxaparin) and unfractionated heparin are advised for use in pregnant women.

Females of childbearing age must be counseled that warfarin is teratogenic and contraindicated during pregnancy and referred for appropriate contraception if needed.

The use of fondaparinux has been reported as a safe and effective alternative for heparin-intolerance pregnant women (e.g., severe allergic reaction to heparin, HIT, and who cannot receive danaparoid).

Females of childbearing age must be counseled that DOACs are not approved for use during pregnancy and referred for appropriate contraception if needed.